Recent papers
Pyramidal cell types and 5-HT2A receptors are essential for psilocybin’s lasting drug action.
Shao LX*, Liao C*, Davoudian PA, Savalia NK, Jiang Q, Wojtasiewicz C, Tan D, Nothnagel JD, Liu RJ, Woodburn SC, Bilash OM, Kim H, Che A, and Kwan AC.
bioRxiv (2024). [Link]
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo.
Shao LX, Liao C, Gregg I, Davoudian PA, Savalia NK, Delagarza K, and Kwan AC.
Neuron (2021). [PDF] [Data and code] [Preview by DiBerto and Roth]
Shared and distinct brain regions targeted for immediate early gene expression by ketamine and psilocybin.
Davoudian PA, Shao LX, and Kwan AC.
ACS Chemical Neuroscience (2023). [PDF] [Data and code] [Gene expression data]
Psilocybin facilitates fear extinction: importance of dose, context, and serotonin receptors.
Woodburn SC, Levitt CM, Koester AM, and Kwan AC.
ACS Chemical Neuroscience (2024). [PDF] [Data]
The neural basis of psychedelic action.
Kwan AC, Olson DE, Preller KH, and Roth BL.
Nature Neuroscience (2022). [PDF]
Full publication list
| Paper | Links | Topic | Type |
|---|---|---|---|
| Pyramidal cell types and 5-HT2A receptors are essential for psilocybin's lasting drug action. Shao LX*, Liao C*, Davoudian PA, Savalia NK, Jiang Q, Wojtasiewicz C, Tan D, Nothnagel JD, Liu RJ, Woodburn SC, Bilash OM, Kim H, Che A, and Kwan AC. bioRxiv. | [Preprint] | Psychiatric drug | Primary research |
| Structural neural plasticity evoked by rapid-acting antidepressant interventions. Liao C, Dua A, Wojtasiewicz C, Liston C, and Kwan AC. Nature Reviews Neuroscience (2024). | [PDF] | Psychiatric drug | Review |
| Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression. Aboharb F*, Davoudian PA*, Shao LX, Liao C, Rzepka GN, Wojtasiewicz C, Indajang J, Dibbs M, Rondeau J, Sherwood AM, Kaye AP, and Kwan AC. bioRxiv. | [Preprint] | Psychiatric drug | Primary research |
| Ventral hippocampal parvalbumin interneurons gate the acute anxiolytic action of the serotonergic psychedelic DOI. Tiwari P, Davoudian PA, Kapri D, Vuruputturi RM, Karaba LA, Sharma M, Zanni G, Balakrishnan A, Chaudhari PR, Pradhan A, Suryavanshi S, Bath KG, Ansorge MS, Fernandez-Ruiz A, Kwan AC, and Vaidya VA. Neuron (2024). | [PDF] | Psychiatric drug | Collaboration |
| Psilocybin facilitates fear extinction: importance of dose, context, and serotonin receptors. Woodburn SC, Levitt CM, Koester AM, and Kwan AC. ACS Chemical Neuroscience (2024). | [PDF] [Data] | Psychiatric drug | Primary research |
| Frontal noradrenergic and cholinergic transients exhibit distinct spatiotemporal dynamics during competitive decision-making. Wang H*, Ortega HK*, Kelly EB, Indajang J, Feng J, Li Y, and Kwan AC. bioRxiv. | [Preprint] | Decision-making | Primary research |
| Change point estimation by the mouse medial frontal cortex during probabilistic reward learning. Murphy CE, Wang H, Ortega HK, Pinto L, Kwan AC, and Atilgan H. bioRxiv. | [Preprint] | Decision-making | Primary research |
| Spatiotemporal organization of prefrontal norepinephrine influences neuronal activity. Glaeser-Khan S*, Savalia NK*, Cressy J, Feng J, Li Y, Kwan AC, and Kaye AP. eNeuro (2024). | [PDF] | Imaging | Collaboration |
| 5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice. Jefferson SJ, Gregg I, Dibbs M, Liao C, Wu H, Davoudian PA, Woodburn SC, Wehrle PH, Sprouse JS, Sherwood AM, Kaye AP, Pittenger C, and Kwan AC. Neuropsychopharmacology (2023). | [PDF] [Data and code] | Psychiatric drug | Primary research |
| Shared and distinct brain regions targeted for immediate early gene expression by ketamine and psilocybin. Davoudian PA, Shao LX, and Kwan AC. ACS Chemical Neuroscience (2023). | [PDF] [Gene list] [Data and code] | Psychiatric drug | Primary research |
| Timing is key for behavioural benefits of psychedelics (News & Views). Woodburn SC and Kwan AC. Nature (2023). | [PDF] | Psychiatric drug | News & Views |
| Dynamic foraging behavior performance is not affected by Scn2a haploinsufficiency. Schamiloglu S, Wu H, Zhou M, Kwan AC, and Bender KJ. eNeuro (2023). | [PDF] | Decision-making | Collaboration |
| Hyperconnectivity of two separate long-range cholinergic systems contributes to the reorganization of the brain functional connectivity during nicotine withdrawal in male mice. Carrette LLG, Kimbrough A, Davoudian PA, Kwan AC, Collazo A, and George O. eNeuro (2023). | [PDF] | Psychiatric drug | Collaboration |
| Competitive and cooperative games for probing the neural basis of social decision-making in animals. Wang H and Kwan AC. Neuroscience and Biobehavioral Reviews (2023). | [PDF] | Decision-making | Review |
| GESIAP: A versatile genetically encoded sensor-based image analysis program. Zheng WS, Zhang Y, Zhu RE, Zhang P, Gupta S, Huang L, Sahoo D, Guo K, Glover ME, Vadodaria KC, Li M, Qian T, Jing M, Feng J, Wan J, Borden PM, Ali F, Kwan AC, Gan L, Lin L, Gage FH, Venton BJ, Marvin JS, Podgorski K, Clinton S, Zhang M, Looger LL, Li Y, and Zhu JJ. bioRxiv. | [Preprint] | Imaging | Collaboration |
| A computational model for learning from repeated traumatic experiences under uncertainty. Kaye AP, Rao MG, Kwan AC, Ressler KJ, and Krystal JH. Cognitive, Affective, and Behavioral Neuroscience (2023). | [PDF] | Decision-making | Collaboration |
| The neural basis of psychedelic action. Kwan AC, Olson DE, Preller KH, and Roth BL. Nature Neuroscience (2022). | [PDF] | Psychiatric drug | Review |
| Psychedelics and neural plasticity: therapeutic implications. Grieco SF, Castrén E, Knudsen GM, Kwan AC, Olson DE, Zuo Y, Holmes TC, and Xu X. Journal of Neuroscience (2022). | [PDF] | Psychiatric drug | Review |
| Pupil correlates of decision variables in mice playing a competitive mixed-strategy game. Wang H, Ortega HK, Atilgan H, Murphy CE, and Kwan AC. eNeuro (2022). | [PDF] [Data and code] | Decision-making | Primary research |
| Primer: Psychedelics. Kelmendi B, Kaye AP, Pittenger C, and Kwan AC. Current Biology (2022). | [PDF] | Psychiatric drug | Review |
| Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward. Zhou WL, Kim K, Ali F, Pittenger ST, Calarco CA, Mineur YS, Ramakrishnan C, Deisseroth K, Kwan AC, and Picciotto MR. Science Advances (2022). | [PDF] | Decision-making | Collaboration |
| Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo. Shao LX, Liao C, Gregg I, Davoudian PA, Savalia NK, Delagarza K, and Kwan AC. Neuron (2021). | [PDF] [Data and code] [Preview] | Psychiatric drug | Primary research |
| A dendrite-focused framework for understanding the actions of ketamine and psychedelics. Savalia NK, Shao LX, and Kwan AC. Trends in Neurosciences (2021). | [PDF] | Psychiatric drug | Review |
| Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation. Ali F, Shao LX, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, and Kwan AC. Molecular Psychiatry (2021). | [PDF] [Data and code] [PreLights] | Primary research | |
| A visuomotor microcircuit in frontal cortex (News & Views). Ortega HK and Kwan AC. Nature Neuroscience (2021). | [PDF] | Decision-making | News & Views |
| Ketamine for a boost of neural plasticity: how, but also when? (Commentary). Wu H, Savalia NK, and Kwan AC. Biological Psychiatry (2021). | [PDF] | Psychiatric drug | News & Views |
| Database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging data. Rupprecht P, Carta S, Hoffmann A, Echizen M, Blot A, Kwan AC, Dan Y, Hofer SB, Kitamura K, Helmchen F, and Friedrich RW. Nature Neuroscience (2021). | [PDF] | Imaging | Collaboration |
| Secondary motor cortex: broadcasting and biasing animal's decisions through long-range circuits. Yang JH and Kwan AC. International Review of Neurobiology (2021). | [PDF] | Decision-making | Review |
| Applying reinforcement learning to rodent stress research. Liao C and Kwan AC. Chronic Stress (2021). | [PDF] | Decision-making | Review |
| Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, and Kwan AC. Nature Communications (2020). | [PDF] [Data and code] | Psychiatric drug | Primary research |
| Interpreting in vivo calcium signals from neuronal cell bodies, axons, and dendrites: a review. Ali F and Kwan AC. Neurophotonics (2020). | [PDF] | Imaging | Review |
| Cumulative effects of social stress on reward-guided actions and prefrontal cortical activity. Barthas F, Hu MY, Siniscalchi MJ, Ali F, Mineur YS, Picciotto MR, and Kwan AC. Biological Psychiatry (2020). | [PDF] [Data and code] [Commentray] | Decision-making | Primary research |
| Nanoscopic visualization of restricted nonvolume cholinergic and monoaminergic transmission with genetically encoded sensors. Zhu PK, Zheng WS, Zhang P, Jing M, Borden PM, Ali F, Guo K, Feng J, Marvin JS, Wang Y, Wan J, Gan L, Kwan AC, Lin L, Looger LL, Li Y, Zhang Y. Nano Letters (2020). | [PDF] | Imaging | Collaboration |
| Parvalbumin-positive neuron loss and amyloid-beta deposits in the frontal cortex of Alzheimer's disease-related mice. Ali F, Baringer SL, Neal A, Choi EY, and Kwan AC. Journal of Alzheimer's Disease (2019). | [PDF] | Primary research | |
| Enhanced population coding for rewarded choices in the medial frontal cortex of the mouse. Siniscalchi MJ, Wang H, and Kwan AC. Cerebral Cortex (2019). | [PDF] [Data and code] | Decision-making | Primary research |
| Same lesson, varied choices by frontal cortex (News & Views). Atilgan H and Kwan AC. Nature Neuroscience (2018). | [PDF] | Decision-making | News & Views |
| Secondary motor cortex: where 'sensory' meets 'motor' in the rodent frontal cortex. Barthas F and Kwan AC. Trends in Neurosciences (2017). | [PDF] | Decision-making | Review |
| Targeted two-photon chemical apoptotic ablation of defined cell types in vivo. Hill RA, Damisah EC, Chen F, Kwan AC, and Grutzendler J. Nature Communications (2017). | [PDF] | Imaging | Collaboration |
| Fast and slow transitions in frontal ensemble activity during flexible sensorimotor behavior. Siniscalchi MJ, Phoumthipphavong V, Ali F, Lozano M, and Kwan AC. Nature Neuroscience (2016). | [PDF] | Decision-making | Primary research |
| Longitudinal effects of ketamine on dendritic architecture in vivo in the mouse medial frontal cortex. Phoumthipphavong V, Barthas F, Hassett S, and Kwan AC. eNeuro (2016). | [PDF] | Psychiatric drug | Primary research |